A Ukrainian drone strike has killed at least 12 people and injured 39 others in Nizhnekamsk, a city deep inside Russia, local authorities said Monday, marking one of the deadliest attacks to hit the country in more than two years.

Nizhnekamsk, which lies more than 600 miles (1,000 kilometers) east of Moscow, is the site of a major, technologically advanced oil refinery, the likely target of the strike.

Videos circulating on social media, and geolocated by CNN, show plumes of smoke rising from an area just outside the city.

This is a developing story and will be updated.