Iran and the United States are continuing mediated talks aimed at ending the conflict, with Iranian media reporting that both sides are exchanging messages and draft proposals to establish a formal framework for an agreement.

Al Jazeera’s correspondent Almigdad Alruhaid reported from Tehran that Pakistani officials were engaged in “intense mediation activity” between the two countries.

The diplomatic push comes as US Secretary of State Marco Rubio said there were “some good signs” for a possible breakthrough. However, US President Donald Trump also warned Washington could take “very drastic” action if Iran refuses to give up its uranium stockpiles.

Here is what we know:

‘War crime’ on medical research centre: Iran has accused the US and Israel of committing a “war crime” by bombing the Pasteur Institute of Iran early in the war, after The Lancet journal warned that the attack severely damaged a key pillar of the country’s public health system.

US forces at ‘peak readiness’: CENTCOM said the USS Abraham Lincoln strike group remains at “peak readiness” in the Arabian Sea, sharing images of warplanes taking off as Washington maintains pressure on Iran amid ongoing mediation efforts.

Palestinian envoy condemns aid blockade: Palestine’s UN envoy Riyad Mansour said Israel is continuing to collectively punish more than two million Palestinians through its blockade on aid and ongoing attacks, warning the world must not become “accustomed to seeing Palestinians killed”.